The company says the proposal will create space for hundreds of its staff to work at the campus.
The Liberal Democrat leader says the UK's pharmaceutical industry is under "attack".
Its decision comes as the industry says there is a lack of government investment and as the US pressures firms to invest there.
The NHS Covid spring booster campaign is under way, but vaccines are also available privately.
Three women who worked on the Oxford AstraZeneca Covid vaccine talk to the BBC about their work.
Lord Storey says he fears Merseyside was "not a high priority" on the government's growth agenda.
The firm scrapped its £450m investment despite the government's offer of support, the government says.
Steve Rotheram says a plan to scrap a £450m manufacturing plant is "deeply disappointing".
The drugs giant blames "protracted" talks with the government as well as differences over funding.